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What is Dupuytren's disease?

Dupuytren's disease, described in the 1830s, corresponds to an abnormal fibrous thickening (called fibrosis) associated with a retraction of the skin.

Osteology of the thumb column
The hand articulates with the distal part of the radius and ulna.
The thumb column includes the scaphoid bone, the trapezium, the 1st metacarpal and the 2 phalanges of the thumb.